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Independent Test
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Independent Test

    >>> Dataset

11 sulfated proteins (CCKN_CANFA, FMOD_BOVIN, FMOD_HUMAN, HIS1_HUMAN, LUM_MOUSE, OMD_HUMAN, PSK1_ORYSI, PSK1_ORYSJ, PSK2_ORYSI, PSK2_ORYSJ, SIAL_HUMAN) contain 31 experimental sulfotyrosine sites from UniProtKB/SwissProt release 55.0, which do not be stored in UniProtKB/SwissProt release 53.0, are used as independent test in this study.

Independent test can be downloaded.

    >>> Evaluation

Three performance measures were used: Sensitivity, Specificity, and Accuracy,as defined below.
Sensitivity (Sn) = TP / (TP+FN), Specificity (Sp) = TN / (TN+FP) and Accuracy (Acc) = (TP + TN) / (TP+FP+TN+FN), where TP, TN, FP and FN are true positive, true negative, false positive and false negative predictions, respectively. The independent test set was used to evaluate the predictive performance of SulfoSite and Sulfinator.


Tools
Modified Residue
Number of test set
Sn
Sp
Pr
Acc
SulfoSite
Tyrosine (Y)
31
52 %
94 %
73 %
84 %
Tyrosine (Y)
31
19 %
80 %
23 %
65 %

 




Bid Lab, Institute of Bioinformatics, National Chiao Tung University , Taiwan.
Contact us:bryan@mail.nctu.edu.tw with questions or comments.
Websites:http://SulfoSite.mbc.nctu.edu.tw